Description

This two-page magazine spread features a detailed molecular visualisation designed to highlight the mechanisms of pain sensitisation in inflammatory bowel disease (IBD). The artwork captures the complex interaction between molecules released due to cell death and nociceptors, emphasising how chronic inflammation triggers a heightened pain response. The visualisation also highlights the cyclical nature of IBD pain: ongoing inflammation perpetuates nerve activation, which in turn exacerbates inflammation, creating a self-sustaining loop of discomfort and tissue damage. This representation aids in understanding how interrupting this vicious cycle could be key to developing targeted therapies for pain relief in IBD patients.