Description
This project serves as a graphical abstract for the paper titled “GPx1 deficiency confers increased susceptibility to ferroptosis in macrophages from individuals with active Crohn’s disease.” The visual representation encapsulates the key findings by illustrating the role of GPx1 in regulating ferroptosis within macrophages, highlighting how its deficiency leads to heightened vulnerability in the context of active Crohn's disease. Through engaging visuals, the abstract aims to succinctly communicate the critical relationship between oxidative stress, macrophage function, and disease susceptibility, thereby facilitating an improved understanding of the underlying mechanisms contributing to this inflammatory condition.